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Special Instruction : No fasting required
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Sample(s) required : Blood, Whole Blood EDTA (3 ml)
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Overview

Absolute Eosinophil Count (AEC)

Absolute Eosinophil Count (AEC)

The Absolute Eosinophil Count (AEC) is a specific component of a complete blood count (CBC) with differential. It measures the exact number of eosinophils present in a cubic millimeter of your blood.


This count is considered more clinically useful than just the percentage of eosinophils, as it provides a true measure of the total population of these cells.

Eosinophils are a type of white blood cell (leukocyte) that plays a key role in the immune system. Their main functions are:


  1. Fighting Parasites: They are mobilized to destroy parasitic infections (such as hookworm or tapeworm).
  2. Modulating Allergic Reactions: They are involved in the inflammatory response associated with allergies and asthma. They contain granules filled with enzymes and toxic proteins that are released to deal with threats.


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Frequently asked questions on " Absolute Eosinophil Count (AEC) "

A high AEC, or eosinophilia (above $500\text{ cells}/\mu\text{L}$), strongly suggests an active immune reaction. The most common causes are: Allergic Conditions: Asthma, eczema, hay fever (allergic rhinitis), or severe drug reactions. Parasitic Infections: Especially by worms or other parasitic organisms.Eosinophilic Disorders: Diseases like eosinophilic esophagitis or hypereosinophilic syndrome (HES).

In asthma, a high AEC often indicates an eosinophilic phenotype (type) of asthma. This knowledge helps guide treatment, as this specific type of asthma often responds well to certain anti-inflammatory medications, including inhaled or oral corticosteroids and newer targeted biologic therapies.

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