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ACTH (ADRENOCORTICOTROPIC HORMONE)

Special Instruction : No fasting required
Parameters covered : 1
Sample(s) required : Serum, Serum (3 ml)
₹1,350 ₹1,700
Home Collection
Lab Visit

Parameters (1)

Overview

ACTH (Adrenocorticotropic Hormone)

ACTH (Adrenocorticotropic Hormone)

The ACTH Test measures the level of Adrenocorticotropic Hormone in your blood. ACTH is a crucial hormone produced by the pituitary gland (located at the base of the brain). Its primary function is to stimulate the adrenal glands (located on top of the kidneys) to produce the stress hormone cortisol.

The ACTH test is essential for diagnosing disorders related to the production of cortisol, specifically diseases that affect the pituitary and adrenal glands. This is often referred to as assessing the Hypothalamic-Pituitary-Adrenal (HPA) axis.

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Pre-test Information
No fasting required
Report Delivery
Next Day
Code
--
Usage
--
Category
Lab Test
Sample Report Download
Not Available
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Frequently asked questions on " ACTH (Adrenocorticotropic Hormone) "

The test is ordered when a patient shows signs of either Cortisol Deficiency: Unexplained weight loss, fatigue, low blood pressure, and low sodium (possible Adrenal Insufficiency). Cortisol Excess: Weight gain (especially around the abdomen and face), skin thinning, and high blood pressure (possible Cushing's Syndrome/Disease).

No. ACTH levels fluctuate significantly following a diurnal rhythm (day-night cycle). Levels are naturally highest in the early morning (around 6 a.m. to 8 a.m.) and fall to their lowest point late at night. Therefore, the ACTH test must be drawn at a specific time of day (usually morning) for accurate interpretation.

They work in a negative feedback loop as part of the HPA axis (Hypothalamic-Pituitary-Adrenal axis): When ACTH stimulates the adrenals, cortisol levels rise. When cortisol levels get high enough, they signal the pituitary to stop producing ACTH. When cortisol levels drop, the pituitary senses this and releases more ACTH.

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