ALKALINE PHOSPHATASE (ALP)

One Test, Two Key Organs: Liver & Bones

Alkaline Phosphatase (ALP) is an enzyme found throughout your body, but it is concentrated primarily in two places: the Liver (specifically the bile ducts) and the Bones.

The ALP Blood Test measures the amount of this enzyme in your bloodstream. Unlike other liver tests (like SGPT), ALP is specialized. It acts as a "flow monitor" for your liver's bile ducts and a "growth monitor" for your bones. High levels usually indicate a blockage in the liver or high activity in bone tissue.

The ALP test is typically included in a Liver Function Test (LFT) or a routine blood panel.

Why Do You Need This Test?

Doctors order the ALP test to differentiate between different types of medical conditions:

1. To Check Liver & Gallbladder Health:

• Blocked Bile Ducts: If a gallstone or tumour blocks the tubes that carry bile, ALP levels shoot up significantly.
• General Screening: Part of a routine Liver Function Test (LFT) to check for hepatitis or cirrhosis.

2. To Check Bone Health:

• Bone Disorders: Conditions that cause bone to break down and regrow (remodel) release ALP. This includes Paget’s disease, Osteomalacia (soft bones), or Vitamin D deficiency.
• Healing Fractures: If you recently broke a bone, your ALP will naturally be high while it heals.

3. Routine Monitoring:

• For patients taking medications that affect the liver.