The Anti-Nuclear Antibody (ANA) test performed using the Indirect Immunofluorescence Assay (ANA) method is the gold standard for screening and diagnosing Systemic Autoimmune Rheumatic Diseases (SARDs), such as Systemic Lupus Erythematosus (SLE).
This test not only confirms the presence of autoantibodies (antibodies attacking self-components) but also provides critical diagnostic clues through the visualization of distinct fluorescence patterns.