The c-ANCA (Cytoplasmic Anti-Neutrophil Cytoplasmic Antibodies) test is a specialized immunological blood test used to detect autoantibodies that target proteins within the cytoplasm of white blood cells. A positive c-ANCA result is highly correlated with the presence of Proteinase 3 (PR3) antibodies.
The detection of c-ANCA PR3 is the primary diagnostic marker for Granulomatosis with Polyangiitis (GPA), a serious autoimmune condition causing inflammation and damage to small blood vessels (vasculitis) throughout the body, particularly in the kidneys and lungs.
At Augmentum Diagnostics, an NABL-Accredited Lab in Delhi, we perform c-ANCA and PR3 testing with high precision to support the urgent diagnosis and management of systemic vasculitis.