The Complement C3 test is a blood test that measures the amount and/or activity of the Complement component 3 (C3) protein in the serum. C3 is the most abundant and central protein in the Complement System.
C3 is an acute phase reactant, meaning its levels can rise during acute inflammation or infection. However, its main clinical significance lies in its consumption during certain diseases. The test is often ordered alongside the C4 Complement test to understand which activation pathway is involved.