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Special Instruction : No fasting required
Parameters covered : 3
Sample(s) required : Serum, Serum ( 3 ml)
₹7,400 ₹9,250
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Lab Visit

Parameters (3)

Overview

Free Light Chain (FLC)

Free Light Chain (FLC)

The Free Light Chain (FLC) Assay is a specialized blood test that simultaneously measures the concentrations of unbound Kappa (kappa) and Lambda (lambda) immunoglobulin light chains circulating in the serum. Immunoglobulins (antibodies) are built by plasma cells, and they all contain two light chains (either Kappa or Lambda). In health, the vast majority are bound within the complete antibody structure. However, in certain diseases, plasma cells produce an excess of one type of light chain that circulates "freely." The FLC assay and the calculation of the Free kappa: lambda Ratio are the cornerstones for the diagnosis and monitoring of plasma cell disorders. At Augmentum Diagnostics, an NABL-Accredited Lab in Delhi, we utilize advanced methods to provide highly sensitive and accurate FLC measurements, essential for managing complex hematological conditions.

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No fasting required
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Frequently asked questions on " Free Light Chain (FLC) "

Yes. The light chains are small proteins that are normally cleared from the blood by the kidneys. In Chronic Kidney Disease (CKD), both Kappa and Lambda levels can rise significantly because of poor renal clearance. However, the kappa: lambda ratio usually remains normal in CKD unless a concurrent monoclonal disorder is present.

Yes. For patients with MM or other plasma cell disorders, the FLC test is crucial for monitoring. A successful treatment should result in the normalization of the kappa: lambda ratio and a significant reduction of the "involved" (overproduced) light chain. A rising abnormal chain level is a strong indicator of disease progression or relapse.

No, fasting is not required for the Free Light Chain blood test.

The FLC assay requires specialized and highly sensitive equipment (typically nephelometry or turbidimetry) and strict calibration. Augmentum Diagnostics is an NABL-Accredited Lab and one of the best pathology labs in Delhi. Our precision in FLC quantification is vital for the early diagnosis and accurate clinical management of hematological malignancies.

To locate the Best Diagnostics Centre Near Me or to find a Blood testing lab near Mahaveer Enclave, Palam, or Dabri, please visit the "Locations" page on the Augmentum Diagnostics website or contact our customer support team for convenient and professional service.

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