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TREPONEMA PALLIDUM HEMAGGLUTINATION ASSAY (TPHA)

Special Instruction : No fasting required
Parameters covered : 0
Sample(s) required : Serum, Serum (3 ml)
₹700 ₹900
Home Collection
Lab Visit

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Overview

Treponema Pallidum Hemagglutination Assay (TPHA)

Treponema Pallidum Hemagglutination Assay (TPHA)

The Treponema Pallidum Hemagglutination Assay (TPHA) is a specific, reliable blood test offered by Augmentum Diagnostics to detect antibodies against Treponema pallidum, the bacterium that causes Syphilis. Syphilis is a serious sexually transmitted infection (STI) that, if left untreated, can lead to severe complications affecting the heart, brain, and nervous system.


The TPHA test is classified as a treponemal test, meaning it directly looks for antibodies against the syphilis-causing organism itself. This makes it an invaluable tool for confirming a syphilis diagnosis and is often used alongside non-treponemal tests (like VDRL or RPR).


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Pre-test Information
No fasting required
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Next Day
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Lab Test
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Frequently asked questions on " Treponema Pallidum Hemagglutination Assay (TPHA) "

Confirmation of Syphilis: TPHA is a highly specific test used to confirm a reactive screening result from a non-treponemal test (like RPR or VDRL). Diagnosing Late-Stage Syphilis: Treponemal antibodies (detected by TPHA) typically remain reactive for life, even after successful treatment. This makes the TPHA test excellent for diagnosing latent or late-stage syphilis. Screening Tool: It is often included in comprehensive STI screening panels, especially for high-risk individuals and in Ante-Natal Care (ANC) to prevent transmission from mother to baby.

TPHA is a Treponemal Test: It detects antibodies specific to the Treponema pallidum organism itself. TPHA is highly specific and usually remains positive for life, even after successful treatment. VDRL/RPR are Non-Treponemal Tests: They detect antibodies against cardiolipin (a substance released from damaged cells). They are good for screening and monitoring treatment, but can sometimes be false positives due to other conditions.

Yes. TPHA (or other treponemal tests) are a critical part of routine Ante-Natal Care (ANC) screening. Detecting syphilis in pregnant women is vital for preventing congenital syphilis, a severe and life-threatening infection that can be transmitted to the baby.

NABL Accredited Accuracy: Our commitment as an NABL Accredited Laboratory ensures the precision of this specific assay, providing confidence in your diagnostic results. High Specificity: The TPHA is highly specific to Treponema pallidum, minimising false positive results often seen with non-treponemal tests due to conditions like lupus or infectious mononucleosis. Comprehensive STI Panel: We offer TPHA as part of a complete suite of STI diagnostics, ensuring thorough and timely health assessment.

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