The Lupus Anticoagulant (LA) Test using dRVVT (Dilute Russell's Viper Venom Time) is the most common and sensitive laboratory method used to screen for and confirm the presence of Lupus Anticoagulants.
Lupus Anticoagulants are a type of antiphospholipid antibody that paradoxically increases the risk of unwanted blood clots (thrombosis) in arteries and veins, despite the antibody's confusing name (Anticoagulant). $\text{LA}$ often targets phospholipid-protein complexes involved in blood clotting.
The dRVVT method is crucial because Russell's Viper Venom directly activates Factor X in the coagulation cascade, making it highly sensitive to the presence of LA antibodies, which interfere with the phospholipid-dependent step.
At Augmentum Diagnostics, an NABL-Accredited Lab in Delhi, including our location near Dwarka, we adhere to international guidelines for the accurate and definitive diagnosis of Antiphospholipid Syndrome (APS).
