The Anti-Nuclear Antibody (ANA) ELISA test is a blood test that detects the presence of antibodies against certain proteins in the nucleus of cells. The ANA test is primarily used to diagnose autoimmune disorders such as lupus, rheumatoid arthritis, and Sjögren’s syndrome, in which the immune system mistakenly attacks healthy cells and tissues in the body. The ANA test is a useful tool for diagnosing these conditions, as the majority of people with autoimmune disorders have detectable levels of ANA in their blood. The test involves taking a small sample of blood, which is then analyzed in a laboratory to determine the levels of ANA. A positive test result indicates that the person has antibodies against certain proteins in the nucleus of cells and may have an autoimmune disorder. However, a positive result does not necessarily mean that the person has an autoimmune disorder, as ANA can also be present in healthy individuals and people with other conditions. Depending on the results of the test and the person’s symptoms, doctors may recommend additional diagnostic tests or treatments to address underlying conditions. Regular monitoring of ANA levels can also be used to track the progression of autoimmune disorders and evaluate the effectiveness of treatment.